CREAM-HD

IS CAFFEINE AN ENVIRONMENTAL MODIFIER IN HUNTINGTON’S DISEASE?

Recruiting

ABOUT

SPONSOR

University Hospital, Lille

PARTICIPANTS

100

The aim of CREAM-HD is to study whether caffeine consumption is associated with the progression of Huntington’s disease. Principal investigator is Clémence Simonin.

Estimated Study Completion Date: March 2023

Ages Eligible for Study:

21 Years and older (Adult, Older Adult)

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

No

Inclusion Criteria

  • HD mutation carriers (>36 CAG)
  • premanifest (total motor UHDRS < 5)
  • estimated time to diagnosis between 3 and 10 years
  • adults older than 21 years (in order to exclude juvenile patients who begin the disease before 21 years)
  • informed consent signed
  • with a social protection

Exclusion Criteria

  • MRI contraindication
  • pregnant and lactating women
  • People under guardianship, trusteeship, deprive of freedom

COUNTRIES

FRANCE

TRIAL SITE:
University Hospital, Lille

Address: 2 Avenue Oscar Lambret, 59000, Lille

CONTACT
Clémence Simonin
Tel: 03 20 44 57 52
clemence.simonin@chru-lille.fr

Recruiting

TRIAL SITE: 
CHU de Amiens

Address: Amiens, France

CONTACT
Clémence Simonin
Tel: 03 20 44 57 52
clemence.simonin@chru-lille.fr

Recruiting

TRIAL SITE: 
CHU de Angers

Address: Angers, France

CONTACT
Clémence Simonin
Tel: 03 20 44 57 52
clemence.simonin@chru-lille.fr

Recruiting

TRIAL SITE:
CHU Pellegrin

Address: Bordeaux, France

CONTACT
Clémence Simonin
Tel: 03 20 44 57 52
clemence.simonin@chru-lille.fr

Recruiting

TRIAL SITE: 
CHU de Grenoble

Address: Grenoble, France

CONTACT
Clémence Simonin
Tel: 03 20 44 57 52
clemence.simonin@chru-lille.fr

Recruiting

TRIAL SITE: 
CHU Montpellier

Address: Montpellier, France

CONTACT
Clémence Simonin
Tel: 03 20 44 57 52
clemence.simonin@chru-lille.fr

Recruiting

TRIAL SITE:
CHU de Nancy

Address: Nancy, France

CONTACT
Clémence Simonin
Tel: 03 20 44 57 52
clemence.simonin@chru-lille.fr

Recruiting

TRIAL SITE: 
AH-HP La Pitié-Salpétrière

Address: Paris 14, France, 75679

CONTACT
Clémence Simonin
Tel: 03 20 44 57 52
clemence.simonin@chru-lille.fr

Recruiting

TRIAL SITE: 
AH-HP, Hôpital Henri Mondor

Address: Paris, France

CONTACT
Clémence Simonin
Tel: 03 20 44 57 52
clemence.simonin@chru-lille.fr

Recruiting

TRIAL SITE:
CHU Purpan

Address: Toulouse, France

CONTACT
Clémence Simonin
Tel: 03 20 44 57 52
clemence.simonin@chru-lille.fr

Recruiting