ONGOING OBSERVATIONAL TRIALS
Before participating in a study, talk to your health care provider and learn about the risks and potential benefits.
Evaluation of the diagnostic performance of Non-Invasive Prenatal Diagnosis (NIPD) for Single Gene Disorders
Enroll-HD is an international study looking at how the disease changes over time in different people. By tracking changes over the years it is hoping to better understand the course of HD.
Collection a high quality CSF (cerebrospinal fluid) samples and matching plasma samples.
This study is using two types of brain scans—Positron Emission Tomography (PET) and Magnetic Resonance Imaging (MRI)—to look for changes in the brain. The goal is to find out how the brain changes at the molecular, functional, and structural levels, from several years before symptom onset to the advanced symptom stage. The study will be done over a three year period (Baseline, Year-1, and Year-2). This called a longitudinal study
JOIN-HD is a worldwide registry for families affected by Juvenile onset Huntington’s Disease (JoHD), which aims to shed light on this diagnosis, bring together those impacted by JoHD, increase awareness and knowledge about this condition, facilitate research and help advocate for better care.
This study wants to confirm if Brain Derived Neurotropic Factor (BDNF) is a good biomarker for HD. The BDNF will be collected and measured from cerebrospinal fluid (CSF).
Creation of an Italian Network of Biobanks of Rare Diseases
This study will look at the Frequency of Selected Single Nucleotide Polymorphisms in Huntington Disease Gene Expansion Carriers.