A STUDY TO EVALUATE THE EFFICACY AND SAFETY OF INTRATHECALLY ADMINISTERED RO7234292 (RG6042) IN PATIENTS WITH MANIFEST HUNTINGTON’S DISEASE
Active, not recruiting
Generation HD1 is a Phase III trial where Huntington’s disease patients get injections in the spine with a drug called Tominersen (previously called RG6042). The drug is aiming to lower the amount of Huntingtin protein in brain cells. Some of the participants get the active drug injected every 2nd months, another group gets the active drug every 4 months and a third group gets injected with a placebo drug. The potential effect of the study will be measured by testing cognitive, motor and social functioning.
Estimated Study Completion Date: 9 July, 2022