PACE-HD

PHYSICAL ACTIVITY AND EXERCISE OUTCOMES IN HUNTINGTON’S DISEASE (PACE-HD)

Status: Unknown

ABOUT

SPONSOR

Cardiff University

PARTICIPANTS

116

PACE-HD is studying whether participants (with early manifest Huntington’s disease) who commit to the physical activity program, manage to follow up and complete the 12 month intervention. The active intervention group will be supervised and encouraged by a trainer/physiotherapist on a regular basis. The results on both motor and cognitive tests, will be compared with a group of around 60 participants who are only monitored doing their physical activities as usual. The aim of the study is to see if HD patients, when being followed up and encouraged in a specialized program for physical activity, follow the program and benefit from the training.

Estimated Study Completion Date: August 31, 2020

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Ages Eligible for Study:

18 Years and older (Adult, Older Adult)

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

No

Inclusion Criteria

  • Diagnosis of Huntington’s disease, confirmed by genetic testing
  • Above the age of 18
  • A participant (current or newly enrolled) in the Enroll-HD study
  • Up to and including stage 2 disease status (TFC 7-13)

Exclusion Criteria

  • Diagnosis of juvenile onset Huntington’s disease
  • History of co-morbid neurological conditions such as multiple sclerosis or stroke
  • Acute orthopaedic conditions (within a month) e.g. ankle sprain or fracture
  • Inability or unwillingness of participant or legal guardian to give written informed consent

GERMANY

TRIAL SITE:
George-Huntington-Institut 

Address: Münster, Germany, 48149.

Active, Not Recruiting

TRIAL SITE: 
Universitätsklinikum Ulm

Address: Ulm, Baden-Württemberg, Germany, 89081

Active, Not Recruiting

SPAIN

TRIAL SITE:
Merce de Deu de la Mare

Address: Barcelona, Spain, 08035

Active, Not Recruiting

TRIAL SITE: 
Fundacion Jimenez Diaz

Address: Madrid, Spain, 28040

Active, Not Recruiting