PACE-HD
PHYSICAL ACTIVITY AND EXERCISE OUTCOMES IN HUNTINGTON’S DISEASE (PACE-HD)
Status: Unknown
ABOUT
SPONSOR
Cardiff University
PARTICIPANTS
116
PACE-HD is studying whether participants (with early manifest Huntington’s disease) who commit to the physical activity program, manage to follow up and complete the 12 month intervention. The active intervention group will be supervised and encouraged by a trainer/physiotherapist on a regular basis. The results on both motor and cognitive tests, will be compared with a group of around 60 participants who are only monitored doing their physical activities as usual. The aim of the study is to see if HD patients, when being followed up and encouraged in a specialized program for physical activity, follow the program and benefit from the training.
Estimated Study Completion Date: August 31, 2020
Ages Eligible for Study:
18 Years and older (Adult, Older Adult)
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria
- Diagnosis of Huntington’s disease, confirmed by genetic testing
- Above the age of 18
- A participant (current or newly enrolled) in the Enroll-HD study
- Up to and including stage 2 disease status (TFC 7-13)
Exclusion Criteria
- Diagnosis of juvenile onset Huntington’s disease
- History of co-morbid neurological conditions such as multiple sclerosis or stroke
- Acute orthopaedic conditions (within a month) e.g. ankle sprain or fracture
- Inability or unwillingness of participant or legal guardian to give written informed consent
GERMANY
TRIAL SITE:
George-Huntington-Institut
Address: Münster, Germany, 48149.
Active, Not Recruiting
TRIAL SITE:
Universitätsklinikum Ulm
Address: Ulm, Baden-Württemberg, Germany, 89081
Active, Not Recruiting
SPAIN
TRIAL SITE:
Merce de Deu de la Mare
Address: Barcelona, Spain, 08035
Active, Not Recruiting
TRIAL SITE:
Fundacion Jimenez Diaz
Address: Madrid, Spain, 28040
